Office of Research, UC Riverside
Office of Technology Commercialization

Featured Technologies

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Recent Technologies

 
The complement immune system is implicated in many acute and chronic inflammatory conditions and autoimmune diseases, including neurological (Alzheimer’s and multiple sclerosis), renal (lupus nephritis and glomerulonephritis), ocular (age-related macular degeneration), and systemic (lupus and rheumatoid arthritis). The complement protein C3d resides covalently attached in inflamed tissues, and it ... Read More

Optical tweezers (OTs) is a commonly used light-based technology with a broad range of applications in studying mechanobiology. While OTs are capable of making force measurements at the pico-Newton level, they cannot be used to provide size and structural information on the object being investigated. The platform technology developed at UCR provides simultaneous measurements of force and physical... Read More

Pluripotent stem cells (PSC) have tremendous potential in regenerative medicine, cell therapy, and drug/toxicant screening, and can increase our understanding of the pathogenesis and treatment of disease. The stem cell industry has accelerated annual growth projections of 20% by 2020. Overall, there is growing demand for culture media that can support rapid growth, survival, and sustain pluripoten... Read More

In 2013, the US economy incurred $215B in damages from counterfeiting and piracy. Since then, it has been growing relentlessly, stifling innovation and revenues. A wide-range of counterfeited integrated circuits (ICs) exist but current detection systems can only distinguish one type. Therefore, an all-inclusive, yet cost-efficient, detection solution is needed to lower the detrimental impacts of c... Read More

Slugs and snails are among the most important invasive agricultural and horticultural pests. They cause crop and yield loss, reduce crop quality, cause product shipment rejection, transmit plant and human pathogens, and increase management costs as new introductions become widespread and established. The most commonly used management options can be toxic to pets and other non target organisms, har... Read More

Due to the complexity of the complement system cascade, biological roles of many signaling receptors are unknown. Additionally, biased ligand binding to cell-bound receptors may lead to selective intracellular effector binding and ligand-specific pathway activation and function. Mechanistic knowledge forms the basis for assay development to explore pharmacology against complement-mediated inflamma... Read More

The CDC estimated that diabetes costed the US $245B in 2012, with 1.7M new diagnoses every year. As the prevalence continues to grow, a better means to monitor diabetes and prevent furthering the condition is needed. Among many complications, foot ulcers are the most common and is a result of constricted blood flow to the lower extremities. There is great traffic in the market for preventing diabe... Read More

Inflammatory Bowel Disease (IBD) is a chronic condition with substantial health and economic costs, affecting 1.3M people in the US. Currently, there is a lack of precise understanding of IBD and therefore, many are misdiagnosed or not even diagnosed at all. There is a high demand for effective and preventative therapies to reduce the burdens of IBD. Most of the time, patients have to resort to su... Read More

FRET (Fluorescence Resonance Energy Transfer) assay measures binding affinities of proteins to visualize their interaction with one another. SUMOs (Small Ubiquitin-related Modifiers) are post-translational modification proteins that are involved in many cellular processes with a distinguished role in transcription inhibition when attached to other proteins. SUMO signaling pathways in conjunction w... Read More

Brassinosteroids are essential plant hormones that control growth and development, in addition to playing a critical role in response to stress and infections. Brassinosteroids also induce ethylene synthesis and are therefore related to senescence and ripening. The major overarching issue involves strictly controlling brassinosteroid response in order to promote growth yet limit other negative eff... Read More

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